Perioperative stroke
The rate of perioperative strokes after carotid endarterectomy is 1%–3%, in specialized centers <1%.
1. Clamping ischemia of CCA in deficient intracranial collateral circulation (circle of Willis)
- alert patient (regional anesthesia): neurologic symptoms such as unconsciousness, loss of speech, paralysis, agitation
- sleeping patient (general anesthesia): e.g. non-pulsating, dark red arterial return, significant changes in EEG or SSEP (somatosensory evoked potentials) to below 50% of baseline despite adequate blood pressure, significant decrease in velocity in the middle cerebral artery
- Recommendation: Before clamping the CCA administer intravenous heparin 3,000 IU - 5,000 IU (weight-adapted)
- -> Insert a lumen-adapted shunt from the common carotid into the internal carotid artery
2. Inadequate reconstruction with flow turbulence
- Caused by: Remaining plaque, elongations, stenotic kinking, distal step in eversion carotid endarterectomy (ECEA)
- Result: turbulent flow activates coagulation (platelet clotting)
- may lead to perioperative strokes and early occlusion
- Prevention: technically flawless reconstruction, supplementary anticoagulation with intravenous heparin 3,000 IU–5,000 IU prevents thrombus formation
- Intraoperative angiography for quality assurance
- -> operative revision/mechanical recanalization
- -> Immediate postoperative intraarterial lysis if cerebral bleeding is reliably ruled out (imaging!); immediate postoperative systemic lysis is contraindicated
3. Embolization by mobilizing plaque material during the dissection phase
- Prevention: subtle no-touch dissection
- -> operative revision/mechanical recanalization, possibly by endovascular technique
4. Inadequate flushing of all afferent and efferent vessels to rinse out stasis clots
- -> operative revision/mechanical recanalization
5. Intimal clamping damage in severe sclerosis of the afferent common carotid artery
- Local dissection stays undetected
- May result in thromboembolism
- -> operative revision/mechanical recanalization