Evidence - Anastomotic technique, gastrointestinal, end-to-end, open, continuous, hand suture, rotation technique

  1. Literature summary

    Three anastomosis configurations are widely accepted when joining lumens in the gastrointestinal tract:

    • End-to-end anastomosis is indicated when both lumens have a similar, sufficiently large diameter and the likelihood of an anastomotic stenosis is minimal.
    • End-to-side anastomosis is preferred when the luminal diameters differ.
    • In ends with small lumens a side-to-side anastomosis produces an anastomosis with a large lumen and thus prevents later anastomotic stenosis.

    Retrospective studies did not demonstrate any benefit for interrupted vs. a continuous suture technique in single-layer sutures. Benefits of the continuous technique include the smaller amount of foreign body material introduced, cost-effectiveness of the procedure, shorter duration of surgery, and uniform adjustment of suture tension along the entire circumference of the anastomosis. This reduces spillage of contaminated material into the surrounding tissue and abscess formation Drawbacks of continuous sutures: If the suture breaks, this will increase the risk of a complete dehiscence, and placing the stitches is less evident.

    The continuous suture technique is suitable only for sections of intestine that can be rotated.

    Edge-to-edge anastomoses benefit from earlier and increased vascularization.
    During the exudative phase, the wound edges will undergo tissue edema. When tying the sutures and pulling on the suture material, keep the tendency of edema in mind. If the sutures are tied too tightly and the suture material is pulled too hard, this will result in secondary ischemia. Anastomoses which are too loose are not leak-proof.

    Absorbable sutures are reasonable because they prevent chronic foreign body reaction and thus do not induce anastomotic stenosis.

    Regarding the suturing technique, adequate distance both from the wound edge and adjacent sutures should be maintained.
    Coating the sutures with doxycycline may increase suture strength.

    Requirements for the suture material: Low tissue trauma, high flexibility, slippage with high knot security, good tissue compatibility, no bulging, no capillarity (wicking effect), high tensile strength with small suture size, specified absorption time, cost-effectiveness. There is no optimal suture that meets the specified requirements.

    For anastomoses in the gastrointestinal tract, absorbable monofilament 4/0 or 3/0 sutures are used; alternatively, for interrupted sutures, braided (coated) absorbable sutures may also be used.

    The most important layer when suturing the four-layered intestinal wall is the submucosa. The submucosa contains the most collagen fibers and is the layer where the vessels course. Sutures that do not include this important tissue layer only serve to appose and have no significant tensile strength.

    In extramucosal sutures, the excess mucosa is compressed together edge-to-edge and the intestinal walls become slightly inverted.

  2. Ongoing trials on this topic

  3. References on this topic

    Bai J, Zhao Y, Liang H, Li J, Zhang C. Indirect comparison between powered and manual circular staplers for left-sided colorectal anastomoses: clinical and economic outcomes in China. Cost Eff Resour Alloc. 2022 Aug 31;20(1):45.

    Talboom K, Greijdanus NG, van Workum F, Ubels S, Rosman C, Hompes R, de Wilt JHW, Tanis PJ; TENTACLE-Rectum working group.. International expert opinion on optimal treatment of anastomotic leakage after rectal cancer resection: a case-vignette study. Int J Colorectal Dis. 2022 Sep;37(9):2049-2059.

    Chen G, Li W, Yu W, Cen D, Wang X, Luo P, Yan J, Chen G, Zhu Y, Zhu L. Application of Overlap Gastroduodenostomy in Billroth I Anastomosis after Totally Laparoscopic Distal Gastrectomy for Gastric Cancer. Can J Gastroenterol Hepatol.  2022 Aug 12;2022:9094934.

    Xing J, Xu K, Liu M, Gao P, Tan F, Yao Z, Zhang N, Yang H, Zhang C, Cui M, Su X. Modified π-shaped esophagojejunostomy in totally laparoscopic total gastrectomy:  a report of 40 consecutive cases from a single center. J Int Med Res. 2022 Aug;50(8):3000605221116328

    Warrier SK, Williams E, Prabhakaran S, Farmer KC, Kong JC. Surgical quality in colorectal anastomosis: the time is overdue in the assessment of anastomotic integrity. ANZ J Surg. 2022 Jul;92(7-8):1598-1599.

    Morgan RB, Shogan BD. The Science of Anastomotic Healing. Semin Colon Rectal Surg. 2022 Jun;33(2).

    Cantay H, Aydin U, Ozaydin I, Anuk T, Tasci SK, Yildiz U, Ermutlu D, Aksoy O. DIFFERENT SURGICAL METHODS IN COLON ANASTOMOSIS: EXPERIMENTAL STUDY. Arq Bras Cir Dig. 2022 Jun 24;35:e1662.

    Rosendorf J, Klicova M, Herrmann I, Anthis A, Cervenkova L, Palek R, Treska V, Liska V. Intestinal Anastomotic Healing: What do We Know About Processes Behind Anastomotic Complications. Front Surg. 2022 Jun 7;9:904810.

    Aizawa M, Yabusaki H, Matsuki A, Bamba T, Nakagawa S. Intracorporeal hand-sewn anastomosis following pylorus-preserving gastrectomy: surgical technique and short-term surgical outcome. Langenbecks Arch Surg. 2022 Jun;407(4):1711-1720.

    Steger J, Jell A, Ficht S, Ostler D, Eblenkamp M, Mela P, Wilhelm D. Systematic Review and Meta-Analysis on Colorectal Anastomotic Techniques. Ther Clin Risk Manag. 2022 May 4;18:523-539.

    Singh R, Najmi HI, Chahal RK, Nikhil D. A Comparative Study of Single-Layered Versus Double-Layered Intestinal Anastomosis. Cureus. 2022 Mar 12;14(3):e23088.

    Varela C, Nassr M, Razak A, Kim NK. Double-layered hand-sewn anastomosis: a valuable resource for the colorectal surgeon. Ann Coloproctol. 2022 Jun;38(3):271-275.

    Würtz HJ, Bundgaard L, Rahr HB, Frostberg E. Anastomosis technique and leakage rates in minimally invasive surgery for right-sided colon cancer. A retrospective national cohort study. Int J Colorectal Dis. 2022 Mar;37(3):701-708.

    Scott-Conner CEH. Chassin's Operative Strategy in General Surgery: An Expositive Atlas, 4th ed. New York, NY, s.l.: Springer New York; 2014.

Reviews

Chaim FHM, Negreiros LMV, Steigleder KM, Siqueira NSN, Genaro LM, Oliveira PSP, Martinez CAR, Ayriz

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