- chronic anal fissure after failed first-line medication therapy
- Surgical therapy can be performed as a first-line treatment if the patient desires it or if there are additional fistulas and/or pronounced secondary morphological changes present.
Note: Lateral internal sphincterotomy, with a success rate of >90%, is the most effective therapy. In German-speaking regions, fissurectomy, with a success rate of 80%, is preferred due to the significantly lower risk of incontinence.
In a fissurectomy, the secondary morphological changes of the fissure are resected, and the base of the fissure is sparingly excised or debrided. Additionally, a wide extra-anal drainage triangle is created to support healing from the inside out. The primary goal of the operation is the removal of inflammatory fibrotic changes that are important for the pathogenesis of the fissure.

